Chapter 21: Mechanical Circulatory Devices

TEE guidance in the selection, placement, and management of mechanical circulatory support devices is described. Device-specific echocardiographic features will be presented with video images.

1

Figures

Assist devices contraindications. These are some contraindications to the insertion of assist devices, including (A,B) a VSD seen in the TG 2C view, (C,D) grade 5 aortic atherosclerosis and a mobile plaque seen in the LAX thoracic aortic view and (E, F) thrombus across a PFO appearing in the ME RV inflow-outflow view.<em> Abbreviations</em>: 2C, two-chamber; Ao, aorta; AoV, aortic valve; LA, left atrium; LAX, long-axis; ME, mid-esophageal; PFO, patent foramen ovale; RA, right atrium; RV, right ventricle; TG, transgastric; VSD, ventricular septal defect. <i class='fa fa-video-camera' aria-hidden='true'></i>

eFigure 21.1

Assist devices contraindications. These are some contraindications to the insertion of assist devices, including (A,B) a VSD seen in the TG 2C view, (C,D) grade 5 aortic atherosclerosis and a mobile plaque seen in the LAX thoracic aortic view and (E, F) thrombus across a PFO appearing in the ME RV inflow-outflow view. Abbreviations: 2C, two-chamber; Ao, aorta; AoV, aortic valve; LA, left atrium; LAX, long-axis; ME, mid-esophageal; PFO, patent foramen ovale; RA, right atrium; RV, right ventricle; TG, transgastric; VSD, ventricular septal defect.

Impella® device contraindications. Some contraindications to using the Impella® device include (A,B) aortic dissection as seen in this UE view of the aorta and (C,D) LV apical thrombus as appears in this ME LAX view.<em> Abbreviations</em>: Ao, aorta; FL, false lumen; LA, left atrium; LAX, long-axis; LV, left ventricle; ME, mid-esophageal; PE, pericardial effusion; TL, true lumen; UE, upper esophageal. <i class='fa fa-video-camera' aria-hidden='true'></i>

eFigure 21.7

Impella® device contraindications. Some contraindications to using the Impella® device include (A,B) aortic dissection as seen in this UE view of the aorta and (C,D) LV apical thrombus as appears in this ME LAX view. Abbreviations: Ao, aorta; FL, false lumen; LA, left atrium; LAX, long-axis; LV, left ventricle; ME, mid-esophageal; PE, pericardial effusion; TL, true lumen; UE, upper esophageal.

Peripheral V-A ECMO. (A) Normal gas exchange. (B) Differential gas exchange. Red blood: reinfused oxygenated blood from the ECMO circuit. Blue blood: venous blood drained by ECMO circuit. Purple blood: relatively deoxygenated blood ejected from the LV in the setting of impaired native lung gas exchange leading to a Harlequin syndrome where the face and upper extremity are blue and the legs are red.<em> Abbreviations</em>: ECMO, extracorporeal membrane oxygenator; LV, left ventricular; V-A, veno-arterial. Adapted from Asija et al.<strong><sup>37</sup></strong>

eFigure 21.17

Peripheral V-A ECMO. (A) Normal gas exchange. (B) Differential gas exchange. Red blood: reinfused oxygenated blood from the ECMO circuit. Blue blood: venous blood drained by ECMO circuit. Purple blood: relatively deoxygenated blood ejected from the LV in the setting of impaired native lung gas exchange leading to a Harlequin syndrome where the face and upper extremity are blue and the legs are red. Abbreviations: ECMO, extracorporeal membrane oxygenator; LV, left ventricular; V-A, veno-arterial. Adapted from Asija et al.37

V-V ECMO cannulation techniques. These diagrams show a few different options for V-V ECMO cannulation, including (A) femoral-jugular, (B) femoral-femoral and (C) dual-lumen cannula. In femoral-femoral cannulation, a distance ≥ 5 cm must separate the tips of the drainage and reinfusion/return cannula to avoid recirculation.<em> Abbreviations</em>: Ao, aorta; ECMO, extra-corporeal membrane oxygenation; HV, hepatic vein; IVC, inferior vena cava; RA, right atrium; RV, right ventricle; SVC, superior vena cava; V-V, veno-venous. Adapted from Banfi<sup>43</sup> and Burrel et al.<sup>96</sup>

eFigure 21.18

V-V ECMO cannulation techniques. These diagrams show a few different options for V-V ECMO cannulation, including (A) femoral-jugular, (B) femoral-femoral and (C) dual-lumen cannula. In femoral-femoral cannulation, a distance ≥ 5 cm must separate the tips of the drainage and reinfusion/return cannula to avoid recirculation. Abbreviations: Ao, aorta; ECMO, extra-corporeal membrane oxygenation; HV, hepatic vein; IVC, inferior vena cava; RA, right atrium; RV, right ventricle; SVC, superior vena cava; V-V, veno-venous. Adapted from Banfi43 and Burrel et al.96

V-V ECMO cannulae position. This CXR shows the multistage access cannula tip positioned at the RA/SVC junction, whereas the return cannula is ≥ 5cm above the proximal drainage hole.<em> Abbreviations</em>: CXR, chest x-ray; ECMO, extracorporeal membrane oxygenation; RA, right atrium; SVC, superior vena cava; V-V, veno-venous. Adapted from the The Alfred ICU (https://www.alfredicu.org.au/) and the Intensive blog (https://intensiveblog.com/ecmo/).

eFigure 21.19

V-V ECMO cannulae position. This CXR shows the multistage access cannula tip positioned at the RA/SVC junction, whereas the return cannula is ≥ 5cm above the proximal drainage hole. Abbreviations: CXR, chest x-ray; ECMO, extracorporeal membrane oxygenation; RA, right atrium; SVC, superior vena cava; V-V, veno-venous. Adapted from the The Alfred ICU (https://www.alfredicu.org.au/) and the Intensive blog (https://intensiveblog.com/ecmo/).

Brain monitoring during ECMO. This is a patient undergoing heart transplantation who required ECMO. (A) Descending aorta biplane and 3D views show air (arrows) in the aortic lumen. (B-D) This was associated with the appearance of HITS in both the left and right cerebral territories (yellow arrows). Following ECMO initiation, the total number of HITS increased significantly on the right from 23 to 1330 and on the left from 39 to 348.<em> Abbreviations</em>: 3D, three-dimensional; Ao, aorta; Diast, diastole; DM%, % percentage of mean velocity changes or delta in relation to the baseline value; ECMO, extra-corporeal membrane oxygenation; HITS, high-intensity transient signals; HR, heart rate MCA, right middle cerebral artery; PI, pulsatility index; RI, resistance index. Adapted from Noel et al. <strong><sup>54</sup></strong> <i class='fa fa-video-camera' aria-hidden='true'></i>

eFigure 21.24

Brain monitoring during ECMO. This is a patient undergoing heart transplantation who required ECMO. (A) Descending aorta biplane and 3D views show air (arrows) in the aortic lumen. (B-D) This was associated with the appearance of HITS in both the left and right cerebral territories (yellow arrows). Following ECMO initiation, the total number of HITS increased significantly on the right from 23 to 1330 and on the left from 39 to 348. Abbreviations: 3D, three-dimensional; Ao, aorta; Diast, diastole; DM%, % percentage of mean velocity changes or delta in relation to the baseline value; ECMO, extra-corporeal membrane oxygenation; HITS, high-intensity transient signals; HR, heart rate MCA, right middle cerebral artery; PI, pulsatility index; RI, resistance index. Adapted from Noel et al. 54

ECMO complication. A 64-year-old man is on a centrifugal pump for cardiogenic shock after heart transplantation. (A, B) ME 4C views show an unexpected LA and LV thrombus attached to the atrial anastomosis site on the third day.<em> Abbreviations</em>: 4C, four chamber; ECMO, extracorporeal membrane oxygenation; LA, left atrium; LV, left ventricle; ME, mid-esophageal; RA, right atrium; RV, right ventricle. <i class='fa fa-video-camera' aria-hidden='true'></i>

eFigure 21.25

ECMO complication. A 64-year-old man is on a centrifugal pump for cardiogenic shock after heart transplantation. (A, B) ME 4C views show an unexpected LA and LV thrombus attached to the atrial anastomosis site on the third day. Abbreviations: 4C, four chamber; ECMO, extracorporeal membrane oxygenation; LA, left atrium; LV, left ventricle; ME, mid-esophageal; RA, right atrium; RV, right ventricle.

LV venting. This algorithm describes LV venting diagnosis and therapeutic options in patients with V-A ECMO.<em> Abbreviations</em>: ECMO, extracorporeal membrane oxygenation; IABP, intra-aortic balloon pump; LA, left atrial; LV, left ventricular; LVEDP, left ventricular end-diastolic pressure; MAP, mean arterial pressure; VA, veno-arterial. Adapted from Ricarte Bratti et al.<strong><sup>98</sup></strong>

eFigure 21.26

LV venting. This algorithm describes LV venting diagnosis and therapeutic options in patients with V-A ECMO. Abbreviations: ECMO, extracorporeal membrane oxygenation; IABP, intra-aortic balloon pump; LA, left atrial; LV, left ventricular; LVEDP, left ventricular end-diastolic pressure; MAP, mean arterial pressure; VA, veno-arterial. Adapted from Ricarte Bratti et al.98

2

Videos

Chapter 21 Fig01A

Chapter 21 Fig01C

Chapter 21 Fig01E

Chapter 21 Fig03A

Chapter 21 Fig03CE

Chapter 21 Fig03E

Chapter 21 Fig04A

Chapter 21 Fig04D

Chapter 21 Fig05A

Chapter 21 Fig05D

Chapter 21 Fig06A

Chapter 21 Fig07A

Chapter 21 Fig07C

Chapter 21 Fig08A

Chapter 21 Fig08C

Chapter 21 Fig08D

Chapter 21 Fig08E

Chapter 21 Fig09A

Chapter 21 Fig09C

Chapter 21 Fig11A

Chapter 21 Fig11C

Chapter 21 Fig11D

Chapter 21 Fig11F

Chapter 21 Fig11G

Chapter 21 Fig11I

Chapter 21 Fig12A

Chapter 21 Fig12E

Chapter 21 Fig13A

Chapter 21 Fig13C

Chapter 21 Fig14A

Chapter 21 Fig14C

Chapter 21 Fig14E

Chapter 21 Fig15A

Chapter 21 Fig15C

Chapter 21 Fig15D

Chapter 21 Fig20BD

Chapter 21 Fig21A

Chapter 21 Fig21E

Chapter 21 Fig22C

Chapter 21 Fig22D

Chapter 21 Fig22F

Chapter 21 Fig22G

Chapter 21 Fig23A

Chapter 21 Fig23D

Chapter 21 Fig24ABCD

Chapter 21 Fig25

Chapter 21 Fig28C

Chapter 21 Fig28F

Chapter 21 Fig29A

Chapter 21 Fig29C

Chapter 21 Fig30A

Chapter 21 Fig30CD

3

Tables

eTable 21.2 Percutaneous Ventricular Assist Devices

DeviceTandemHeartTMImpella®
ManufacturerCardiacAssist, Inc., Pittsburgh, Pennsylvania, U.S.Abiomed, Inc., Danvers, Massachusetts, U.S.
ApprovalCE Mark, FDA 2003CE Mark, Canada, FDA 2007
CannulaVenous drainage, arterial outflowArterial only
PumpCentrifugal, extracorporealAxial flow, intracorporeal
CircuitVenous transseptal catheter in LA aspirates blood into pump and delivers into femoral arteryRetrograde aortic catheter in LV through AoV aspirates blood from LV below valve and delivers into the ascending aorta above valve
ContraindicationsRV failure (for left-sided devices), VSD, AR, PVDMechanical AoV, calcific aortic stenosis, PVD
AnticoagulationACT > 300 s during insertion, Maintain ACT > 200 or use anti-Xa measurementMaintain ACT > 160 ms
Hemodynamic effects↑MAP, ↑CO, ↓afterload, ↓preload, ↑MVO2↑MAP, ↑CO, ↓PCWP
ComplicationsCannula trauma (cardiac perforation), thromboembolism, hypothermia, bleeding, infectionDevice malfunction, bleeding, infection, thrombus
Abbreviations: ACT, activated clotting time; AoV, aortic valve; AR, aortic regurgitation; CE, European Community; CO, cardiac output; FDA, Food and Drug Administration; LA, left atrium; LV, left ventricle; MAP, mean arterial pressure; MVO2, myocardial oxygen consumption; PCWP, pulmonary capillary wedge pressure; PVD, peripheral vascular disease; RV, right ventricle; VSD, ventricular septal defect. Source: Adapted from Vegas et al .88